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In 2011, Yuichiro Kanno of Toho University published the results of an initial study on YK11, confirming that the rare compound was a SARM.
YK11 attaches itself to the AR (androgen receptor), but only inducts methods that lead to the traditional side effects of androgens such as growth of body hair and prostate and enhanced aggression - to a restricted degree.
Most SARMS have quite limited androgenic side effects, but frequently only quite few anabolic effects when likened to testoste. But, this doesn't occur for YK11 as reported in Biological and Pharmaceutical Bulletin in 2013.
Kanno tested C2C12 muscle cells and not lab animals or humans. It has been discovered that muscle
cells produce more anabolic factors if exposed to 500 nmol (nanomoles) YK11 than if you expose the
same muscle cells to 500 nmol DHT.
YK11 induces muscle cells to make more follistatin (more than DHT does) - a strong myostatin inhibitor. YK11 works through the androgen receptor.
With that said, YK11 can be as good as testoster in terms of muscle strengthening, but minus the
detrimental side effects.
SARM YK-11 is one of the most powerful S.A.R.M.S (Selective Androgen Receptor Modulator) on the market today. It is used to achieve Anabolic Steroid type results, but without the negative side effects and legality issues.This particular SARM "YK-11" is for helping the user Gain Lean Muscle Tissue and Lose Fat simultaneously.
YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won't have androgenic side affects like hair loss, acne, etc. The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic growth properties of YK11.
YK11 shows a lot of promise as an apt anabolic SARM. With the muscle growth potential it brings, it's as effective as anabolic steroids and prohormones without the unwanted side effects connected to the latter.SARM YK-11 is a powerful SARM supplement promoting massive lean muscle gains which is a great benefit for those wanting to have an aesthetic and shredded physique!
We expect YK11 to be more potent than SARM LGD in terms of overall growth and feel. At this time, we expect this to be the strongest SARM on the market at a regular dosing. While suppression can occur, we expect this product to have low androgenic properties and can be used by both men and women. From our experience with SARMs, we find there are less losses of on-cycle results than pro-hormones, although typically not as potent. We do expect this product to have similar results as a moderately dosed Halodrol, without the alpha-male/androgenic feelings while on it.
In direct comparison to to LGD-4033 as the reference for assay upon animal models of anabolism and androgenicity, YK-11 demonstrated higher efficacy withing anabolic parameters and lesser androgenicity at equivalent dosages.
It induces muscle cells to make more follistatin which is a strong myostatin inhibitor. Myostatin (also known as growth differentiation factor 8, is a myokine (protein) produced by muscle cells that acts on muscle cells to inhibit myogenesis. Myogenesis is muscle cell growth and differentiation. Research through the years show that when you block myostatin, it allows for significantly more muscle mass. So in research myostatin inhibitors are researched to find cures for muscle diseases.
Recommended maximum dose YK11 is require dosages of 2.0-5.0mg b.i.d. in males and 0.5mg-2mg b.i.d. in females to achieve optimal effects in humans for the noted indications.
|GHRP-6||IGF-1 LR3||Anastrozole (Arimidex)|
|CJC-1295 with DAC||IGF-1 DES||Boldenone|
|CJC-1295 NO DAC||Follistatin||Boldenone undecylenate (EQ)|
|Thymosin β4 (TB500)||EPO||Nolvadex|
|Melanotan-II (MT-II)||Tadalafil (Cialis)|
|Melanotan-I (MT-I)||SARM||Letrozole (Femara)|
|Triptorelin||LGD-4033 (Ligandrol)||Methenolone Acetate|
|GHRH||YK-11||Stanozolol Coarse (Winstrol)|
|Tesamorelin||Aicar||Stanozolol Micronized (Winstrol)|
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