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hgh growth factor,
igf muscle growth
Cas No. 946870-92-4
Synonyms: Insulin-Like Growth Factor-I LR3
Appearance: White Powder
Bacterial Endotoxins: < 5EU/mg
IGF-1 LR3, also known as Long R3 Insulin-like Growth Factor-I with 83 amino acids, is a human recombinant, single, non-glycosylated analog of IGF-I with the substitution of an Arginine (Arg) for the Glutamic Acid (Glu) at position 3, as well as a 13 amino acid extension peptide. This sequence change causes IGF-1 to avoid binding to proteins and allow it to have a much longer half life, around 20-30 hours. Due to this, it has been suggested that IGF-1 LR3 is more potent than the IGF-1 in many aspects such as increasing amino acid transport to cells, increasing glucose transport, increasing protein synthesis, decreasing protein degradation and so on.
IGF-1 belongs to the peptide family which has a same structure and size as insulin. It is a highly anabolic hormone that is released in the liver as well as in the peripheral tissues in response to the GH so that a new muscle could be built. The main work of IGF-1 is to build new muscle tissues by promoting nitrogen retention and protein synthesis. IGF-1 not only makes muscle fibers bigger, but also makes more of them. IGF-1 has potent effect on fat metabolism and helps the body to burn fat rapidly. It also improves mental functions such as reflexes and learning ability.
IGF-1 has a very sensitive and unstable property that's why it is used rarely because it has a very short term life of only 10 minutes. That's why a substitute of IGF-1 referred to as Long R3IGF-1 or IGF-1 LR3 is used. IGF-1 LR3 has longer life. IGF-1 life time is increased from 10 minutes to hours in IGF-1 LR3, so that the users can get away using a smaller amount of IGF-1 LR3 and does not have to use it as frequent. Long R3IGF-1 is in the form of lyophilized powder form or already reconstituted form.
IGF-1 LR3 greatly boosts muscle mass by inducing a state of muscle hyperplasia (increase in number of new muscle cells) in the MUSCLE WHERE ITS INJECTED! So think of it as muscle cell proliferation, or even the splitting of the cell so 1 becomes 2… That’s why its perfect on cycle when you get increased muscle cell growth too. But why is IGF better than HGH? The reason being is HGH causes IGF levels to rise in the liver first, then then the muscle, Whereas IGF-LR3 causes localized IGF levels to rocket.
Igf1-lr3 As you all know is the long acting version of Igf-1, Taking its active potential up towards 20 hours, But along with its ability to stimulate the growth of satellite muscle cells and helping them to mature into new muscle fibers it holds the ability to increase the uptake of many supplements we currently use, And it can cause the enhanced recovery of testicle size, and prevent muscle loss even in PCT. Plus another reason its so potent is because of the decreased binding of Long R3 IGF-1 to all known IGF binding proteins. These binding proteins normally inhibit the biological actions of IGF.. not so with this long acting version.
IG-F1 vs. HG-H
Why IG-F1 and not GH? Growth hormone actually is a precursor to IG-F1 Growth hormone does not directly cause muscle growth, but indirectly causes muscle growth by signaling the release of IG-F1.Human Growth Hormone (HG-H) can be very expensive, and to see muscle growth it needs to be paired with insulin or other anabolic steroids. This makes IG-F1 variants like LR3 and DES, which can be used as a standalone drug, a much more viable option for bodybuilder looking to see solid recovery of damaged tissue and muscle growth.
Another concern with methyl 1-test (and methylated steroids in general) is hepatotoxicity. Other substances that are toxic to the liver (such as alcohol) should be avoided to avoid placing extra stress on the liver. Milk thistle, alpha lipoic acid, and N-acetyl-cysteine are commonly recommended to help protect the liver.
When taking methyl 1-test, it is best to start out with at least a week at a dose of 5-10 mg to see how you react. Many find a lower dose to be just as effective as a higher one, but with less side effects. Most seem to find their ideal dose to be in the 10-30 mg range. Cycle length should be kept short, in the range of 1-4 weeks.
IGF-1 LR3 doses range from 20mcg up to 120mcg. The initial starting dosage is 20-40 mcg. According to the reports of users, the results of Long R3IGF-1 are seen in a shorter span of time. The course length is usually 4 weeks but you can go up to 50 days off. Ideally it should be injected post workout. Injecting the drug intramuscularly is the best option i.e. injecting 20mcg into one bicep and 20mcg into the other. IGF-1 LR3 however has some adverse side effects, which include severe headache, nausea, and possible hypoglycaemia. The drug is not prescribed for persons with a history of cancer.
|GHRP-6||IGF-1 LR3||Anastrozole (Arimidex)|
|CJC-1295 with DAC||IGF-1 DES||Boldenone|
|CJC-1295 NO DAC||Follistatin||Boldenone undecylenate (EQ)|
|Thymosin β4 (TB500)||EPO||Nolvadex|
|Melanotan-II (MT-II)||Tadalafil (Cialis)|
|Melanotan-I (MT-I)||SARM||Letrozole (Femara)|
|Triptorelin||LGD-4033 (Ligandrol)||Methenolone Acetate|
|GHRH||YK-11||Stanozolol Coarse (Winstrol)|
|Tesamorelin||Aicar||Stanozolol Micronized (Winstrol)|
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