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Nootropic Raw Materials Powder Sunifiram / Piperazine CAS 314728-85-3 Safe Brain Supplements

Just completed an order with Peter and his service is A+++. I have posted it elsewhere on the board. I did a gh serum test with his gh and it comes back more 30, crazy high score for 10iu.

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Nootropic Raw Materials Powder Sunifiram / Piperazine CAS 314728-85-3 Safe Brain Supplements

China Nootropic Raw Materials Powder Sunifiram / Piperazine CAS 314728-85-3 Safe Brain Supplements supplier

Large Image :  Nootropic Raw Materials Powder Sunifiram / Piperazine CAS 314728-85-3 Safe Brain Supplements

Product Details:

Place of Origin: China
Brand Name: SGH
Certification: GMP, ISO9001,BRC,KOSHER
Model Number: 314728-85-3

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiation
Packaging Details: Discreet package or foiled bag or pack as customer's request
Payment Terms: T/T, Western Union, MoneyGram, Bitcoin
Supply Ability: 100kg/Month
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Detailed Product Description
CAS NO: 314728-85-3 Synonyms: Piperazine
Form: Powder Usage: Loss Weight
Color: White Storage: -20C

Detailed Product Description
Product Name: Sunifiram Catagory: Nootropic Raw Powder
Appearance: White Powder CAS No.: 314728-85-3
Purity: 99% Min Shipping Method: EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC
 

 

 

Nootropic Raw Materials Powder Sunifiram / Piperazine, 1-benzoyl-4-(1-oxopropyl)- Pharmaceutical Chemical

 

 

Piperazine, 1-benzoyl-4-(1-oxopropyl)-

 

Nootropic Raw Materials Powder Sunifiram / Piperazine, 1-benzoyl-4-(1-oxopropyl)- Pharmaceutical Chemical
 

CAS: 314728-85-3

MF: C14H18N2O2

MW: 246.30492

Synonyms: Piperazine, 1-benzoyl-4-(1-oxopropyl)-;SunifiraM;1-(4-Benzoyl-1-piperazinyl)-1-propanone;1-Benzoyl-4-(1-oxopropyl)-piperazine;1-(4-Benzoylpiperazin-1-yl)propan-1-one;1-Benzoyl-4-propanoylpiperazine;Sunifiram DM235

 
 
Properties
 

Density 1.154±0.06 g/cm3 (20 ºC 760 Torr)

solubility H2O: soluble24mg/mL

color white

 

 

Abstract

 

This compound is known as an AMPAkine due to exerting most of its actions via the AMPA receptor (one of the three main subsets of glutamate receptors, alongside NDMA and kainate). This enhancement of AMPA function seems to also rely on enhancing signalling via the Glycine binding site of NMDA receptors, although one minimal signalling goes through the NMDA receptor then the benefits on AMPA receptors seem dose-dependent.

Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232).


Sunifiram operates by activating AMPA receptors; that is, the receptors that are responsible for the mediation of synaptic transmission in the central nervous system. Its mechanics also increases phosphorylation of AMPAR and NMDAR through protein kinase activation, which in turn enhances long-term potentiation - that is, an enhancement in signal transmission between two neurons resulting from simultaneous stimulation.


The kinase activation that is influenced by Sunifiram also improves cognitive defects. Additionally, Sunifiram works in the cerebral cortex of animal test subjects by assisting in the release of acetylcholine, the organic molecule that acts as a neurotransmitter in a host of various organisms. These operational mechanisms enable Sunifiram to exert anti-amnesiac properties.

 

 

 

 

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