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Cas No. 87616-84-0
Synonyms: GHRP-6 Acetate
Molecular Formula: C46H56N12O6
Bacterial Endotoxins: < 5EU/mg
GHRP-6, a peptide with sequence H(d-W)AW(d-F)K-NH2, is a ghrelin receptor agonist, which has previously been reported to increase gastric emptying in normal rats. A study investigated the prokinetic effect of GHRP-6 in a mouse model of diabetes mellitus have shown that GHRP-6 can accelerate delayed gastric emptying (GE) and intestinal transit (IT), but has no effect on colonic transit (CT) in diabetic mice, which implied that GHRP-6 may exert its prokinetic effects via the cholinergic pathway in the enteric nervous system, and therefore, may have therapeutic potential for diabetic patients with delayed upper gastrointestinal transit.
GHRP-6 is a potent stimulator of natural release. GHRP-6 is a Hexa-peptide that promotes food intake by stimulating hunger and helps increase energy metabolism. Releasing Peptides, similar to GHRP-6, are most commonly used for treatment of (GH) deficiencies, eating disorders, obesity, etc. Research has shown that use of these Peptides increases lean muscle mass, strength, stamina and decreases body fat.
GHRPs are not simply surrogates of GHRH, instead GHRP-6 is an artificial activator of a separate newly discovered receptor called Secretagogue Receptor (GHS-R). Soon Ghrelin was discovered, the endogenous ligand that binds to the GHS-R. Both Ghrelin and all the synthetic compounds such as GHRP-6 were termed "Secretagogues" (GHSs). One side effect of GHRP-6 is a significant increase in appetite due to stimulating the release of Ghrelin, a peptide that is released naturally in the lining of the stomach that increases hunger and gastric emptying. Also, GHRP-6 causes stimulation of the anterior pituitary gland which causes an increase in release. The increased amounts of can cause the liver to secrete the , which improves the animal body's ability to burn fat and build muscle. Since GHRP-6 acts directly on the feedback loop which signals the inhibition release, GHRP-6 can re-stimulate the production Hormone.
|GHRP-6||IGF-1 LR3||Anastrozole (Arimidex)|
|CJC-1295 with DAC||IGF-1 DES||Boldenone|
|CJC-1295 NO DAC||Follistatin||Boldenone undecylenate (EQ)|
|Thymosin β4 (TB500)||EPO||Nolvadex|
|Melanotan-II (MT-II)||Tadalafil (Cialis)|
|Melanotan-I (MT-I)||SARM||Letrozole (Femara)|
|Triptorelin||LGD-4033 (Ligandrol)||Methenolone Acetate|
|GHRH||YK-11||Stanozolol Coarse (Winstrol)|
|Tesamorelin||Aicar||Stanozolol Micronized (Winstrol)|